What is DeSci?

11/25/2024, 3:01:41 AM
DeSci (Decentralized Science) aims to create a public infrastructure for scientific research by leveraging Web3 technologies.

Challenges in Traditional Science

Traditional scientific research (TradSci) has contributed immensely to human progress but is not without its limitations. Some of the key issues often encountered include:

  1. Restricted Access: Most scientific papers are locked behind paywalls or subscription fees, limiting access to critical knowledge. This makes it harder for researchers to stay updated.
  2. Lack of Collaboration: Research is often conducted in silos, with individual teams working independently. This fragmentation slows down discovery and innovation.
  3. Centralized Funding: Research funding is typically controlled by centralized institutions or grant agencies, leading to inefficiencies and subjective decision-making in resource allocation.
  4. Transparency Deficits: Peer reviews, research data, and funding processes often lack transparency, which can erode trust in scientific outcomes.
    A common analogy in traditional science is the “Valley of Death,” referring to the critical phase between foundational scientific research and successful innovation that benefits society—particularly patients.

What is Decentralized Science (DeSci)?

DeSci (Decentralized Science) aims to create a public infrastructure for scientific research by leveraging Web3 technologies. It seeks to fund, produce, review, verify, store, and disseminate scientific knowledge in a decentralized manner. The ultimate goal of DeSci is to foster an ecosystem that incentivizes scientists to openly share their findings, facilitates transparent peer review processes, and allows anyone to contribute to or access research. This decentralized approach eliminates reliance on central institutions.

How Does DeSci Transform Science?

  1. Addressing Restricted Access:
    DeSci improves accessibility through blockchain-based research repositories. Scientists can share their findings as NFTs, benefiting directly from their work while promoting knowledge dissemination. Additionally, blockchain-based storage ensures data security and accessibility.
  2. Enhancing Collaboration:
    DeSci provides a global platform for collaboration, breaking down the silos in traditional science. By using blockchain and smart contracts, researchers can share data, tools, and resources seamlessly, accelerating innovation.
  3. Decentralized Funding:
    DeSci leverages Decentralized Autonomous Organizations (DAOs) and smart contracts to distribute research funding transparently and equitably. Scientists can crowdfund through tokenized projects, and contributors are rewarded based on the quality and impact of their work. This ensures the most promising projects receive the attention they deserve.
  4. Increasing Transparency:
    DeSci uses blockchain to log every research activity and decision-making process, increasing transparency in data storage, peer reviews, and funding allocations. This openness fosters public trust in science and reduces the likelihood of bias or unethical practices.

RIF

RIF represents Rifamycin, introduced by Pump.science—a meme-launching platform under Solana-based DeSci initiative Molecule DAO. It serves as a tokenized prediction game for lifespan-extension experiments. Traditionally known as Rifampin, RIF is an antibiotic primarily used to treat infections like tuberculosis. In prior trials, it extended the lifespan of worms by 32.87%.

URO

URO, also from Pump.science, represents Urolithin, which extended lifespan by 6.35% in earlier experiments. It promotes autophagy and improves mitochondrial function, contributing to cellular health and anti-aging. By repairing cellular damage, Urolithin A has the potential to delay aging and improve overall health.

SCIHUB

The SCIHUB token aligns with the concept of scientific donations and free access to knowledge. Inspired by the platform Sci-Hub, which provides free access to millions of academic papers, it represents decentralized science. While Sci-Hub is praised for democratizing knowledge, critics argue it bypasses copyright laws and challenges publishers’ rights.

Conclusion

DeSci is an emerging field with immense potential to revolutionize science. By addressing challenges in TradSci, DeSci could attract traditional academic institutions to its vision. A scientific ecosystem that prioritizes transparency, collaboration, and fairness is the ideal, and DeSci aims to make this a reality.

* The information is not intended to be and does not constitute financial advice or any other recommendation of any sort offered or endorsed by Gate.
* This article may not be reproduced, transmitted or copied without referencing Gate. Contravention is an infringement of Copyright Act and may be subject to legal action.

Share

Crypto Calendar

Project Updates
Etherex will launch the token REX on August 6.
REX
22.27%
2025-08-06
Rare Dev & Governance Day in Las Vegas
Cardano will host the Rare Dev & Governance Day in Las Vegas, from August 6 to 7, featuring workshops, hackathons and panel discussions focused on technical development and governance topics.
ADA
-3.44%
2025-08-06
Blockchain.Rio in Rio De Janeiro
Stellar will participate in the Blockchain.Rio conference, scheduled to be held in Rio de Janeiro, from August 5 to 7. The program will include keynotes and panel discussions featuring representatives of the Stellar ecosystem in collaboration with partners Cheesecake Labs and NearX.
XLM
-3.18%
2025-08-06
Webinar
Circle has announced a live Executive Insights webinar titled “The GENIUS Act Era Begins”, scheduled for August 7, 2025, at 14:00 UTC. The session will explore the implications of the newly passed GENIUS Act—the first federal regulatory framework for payment stablecoins in the United States. Circle’s Dante Disparte and Corey Then will lead the discussion on how the legislation impacts digital asset innovation, regulatory clarity, and the US’s leadership in global financial infrastructure.
USDC
-0.03%
2025-08-06
AMA on X
Ankr will host an AMA on X on August 7th at 16:00 UTC, focusing on DogeOS’s work in building the application layer for DOGE.
ANKR
-3.23%
2025-08-06

Related Articles

DOGS Token Overview: Tokenomics and Airdrop Claiming (as of 2025)
Advanced

DOGS Token Overview: Tokenomics and Airdrop Claiming (as of 2025)

The DOGS token, inspired by the mascot Spotty designed by TON founder Pavel Durov for the Telegram community, embodies the unique spirit and culture of the Telegram ecosystem. As of 2025, DOGS has established itself as a leading meme token on the TON blockchain, ranking in the top 50 cryptocurrencies by market cap. The ecosystem has expanded significantly, featuring DOGS 2.0 protocol with enhanced staking, DeFi integrations across multiple chains, and a community governance system. DOGS now supports NFT collections, gaming integrations, and cross-chain functionality, with Gate providing comprehensive trading support and improved liquidity options.
5/22/2025, 3:02:50 AM
Gate.io Launches Pilot Trading Section: Capture On-chain Alpha and Seize 100x Opportunities!
Advanced

Gate.io Launches Pilot Trading Section: Capture On-chain Alpha and Seize 100x Opportunities!

The Gate.io Pilot Trading Section is a newly launched independent trading board focused on finding popular on-chain projects. It helps users participate in on-chain project launches without needing a Web3 wallet.
9/14/2024, 6:35:55 AM
Grass (GRASS) — Decentralized AI Data Collection
Advanced

Grass (GRASS) — Decentralized AI Data Collection

Grass is a DePIN project built on the Solana network that leverages unused internet bandwidth to gather information from public networks. This information is then used to train large language models (LLMs) and establish a transparent data marketplace that rewards all participants. The protocol utilizes the bandwidth of users' devices to search for necessary information, process the collected data, and record its provenance history on the blockchain using zero-knowledge proofs (ZKPs).
11/4/2024, 6:54:01 AM
Virtuals Protocol (VIRTUAL) — The AI Agent Generation Platform at the Forefront of Innovation
Beginner

Virtuals Protocol (VIRTUAL) — The AI Agent Generation Platform at the Forefront of Innovation

Founded in 2021, Virtuals Protocol is an AI agent generation platform built on Base Rollup. It was co-founded by Prakash Somosundram, Colin Choo, Christopher Johnson, and Matthew. The platform aims to allow anyone to create an AI agent—a virtual character capable of interacting with and participating in its environment like a human. It incentivizes the decentralized creation and monetization of AI agents for every virtual interaction, whether in gaming, the metaverse, online engagements, or other applications.
12/18/2024, 8:57:22 AM
Kaito (KAITO) - A Decentralized InfoFi Platform
Beginner

Kaito (KAITO) - A Decentralized InfoFi Platform

Kaito is a decentralized application platform based on Web3 and AI technologies, aimed at providing users with low-barrier personalized AI robot creation tools and building an open and fair AI content ecosystem.
2/28/2025, 7:34:54 AM
Gate.io Launches PreMint: A Revolution in Pre-Market Trading
Advanced

Gate.io Launches PreMint: A Revolution in Pre-Market Trading

Gate.io recently launched PreMint feature for pre-market trading. PreMint is a staking and minting mechanism for pre-market trading. It allows users to stake USDT to mint PreToken.
9/3/2024, 3:58:28 AM
Start Now
Sign up and get a
$100
Voucher!